Which certifications do UniCare's manufacturing partners hold?

UniCare works with Chinese manufacturers whose quality systems are certified to standards including GMP, EU-GMP, CEP, ISO 9001, ISO 22000 and HACCP. Certification scope varies by product line, and the relevant certificates are shared for each ingredient during supplier qualification.

How are UniCare botanical extracts tested before release?

Each partner factory has independent testing capability. Typical release testing covers marker compound assay by HPLC or UV, residual solvents by GC, pesticide residues by GC-MS/MS, heavy metals (lead, arsenic, mercury, cadmium, copper) by ICP-MS, microscopic and TLC identification, moisture or loss on drying, ash, microbial limits, pH, conductivity and sulfur dioxide residue.

What documents are supplied with each batch?

Each lot is supplied with a batch-specific Certificate of Analysis. Specification sheets, MSDS, methods of analysis and regulatory statements can be provided on request during qualification.

Can UniCare customize ingredient specifications?

Yes. The customized service covers adjustments such as assay level or extract ratio, particle size and packaging format, subject to technical feasibility and regulatory requirements in the destination market.

How can buyers request a catalog or samples?

Buyers can request the product catalog and samples through the Request a Catalog page, by email at info@unicare-bio.com, or by phone at +86-028-85333989.

Best Ginseng Extract Suppliers, Factories

1 / 1

Best Ginseng Extract Suppliers, Factories

Production Method: Extraction
Source: Panax Ginseng C.A. Mey, Panax quinquefolium L. etc.
Appearance: Brown Powder
Main Active Ingredient: Ginsenoside Rg1, Re, Rf, Rb1, Rc, Rb2, Rd.

Specifications:

Ginsenosides 80% (UV),
Ginsenosides 3-45% (HPLC)

Send Inquiry

Product Description

Ginseng Extract: Benefits and Mechanisms

Ginseng Extract is derived from the root of the Panax ginseng plant, also known as Korean ginseng or Asian ginseng. It has been used for centuries in traditional medicine, particularly in Asia, for its numerous health benefits. The primary active components of Panax ginseng are ginsenosides, which are responsible for its therapeutic effects.

Ginsenosides 80% (UV)

Ginsenosides 3-45% (HPLC)

Key Components of Panax Ginseng Extract

Ginsenosides

These are the main active compounds in Ginseng Extract, responsible for its wide range of pharmacological effects. Ginsenosides are classified into various types, including Rb1, Rb2, Rc, Rd, Re, and Rg1, each contributing to different therapeutic benefits.

Polysaccharides

These compounds contribute to the immune-boosting and anti-inflammatory properties of the extract.

Peptides and Polyacetylenes

These components play a role in the overall health benefits of Panax ginseng, including its antioxit and anti-inflammatory effects.

Chemical Structure & Identification

Ginsenoside Rg₁

CAS number: 22427-39-0

Molecular Formula: C₄₂H₇₂O₁₄

Molecular Weight: 801.01

Structural Formula:

Ginsenoside Re

CAS number: 52286-59-6

Molecular Formula: C₄₈H₈₂O₁₈

Molecular Weight: 947.15

Structural Formula:

Ginsenoside Rf

CAS number: 52286-58-5

Molecular Formula: C₄₂H₇₂O₁₄

Molecular Weight: 801.01

Structural Formula:

Ginsenoside Rb₁

CAS number: 41753-43-9

Molecular Formula: C₅₄H₉₂O₂₃

Molecular Weight: 1109.29

Structural Formula:

Ginsenoside Rc

CAS number: 11021-14-0

Molecular Formula: C₅₃H₉₀O₂₂

Molecular Weight: 1079.27

Structural Formula:

Ginsenoside Rb₂

CAS number: 11021-13-9

Molecular Formula: C₅₃H₉₀O₂₂

Molecular Weight: 1079.27

Structural Formula:

Ginsenoside Rd

CAS number: 52705-93-8

Molecular Formula: C₄₈H₈₂O₁₈

Molecular Weight: 947.15

Structural Formula:

Health Benefits & Scientific Mechanisms

Improved Cognitive Function

Mechanism: Ginseng Extract enhances cognitive function by increasing the release of neurotransmitters and improving synaptic plasticity. Ginsenosides also promote neurogenesis and protect against neuroinflammation.

Supporting Evidence: A study published in "Journal of Ginseng Research" (2016) demonstrated that ginseng extract improved cognitive performance and memory in animal models (Kennedy et al., 2016). Another study in "Phytotherapy Research" (2012) showed that ginseng extract supplementation improved mental performance and reduced mental fatigue in healthy adults (Reay et al., 2012).

Anti-inflammatory Effects

Mechanism: Ginsenosides in Ginseng Extract modulate inflammatory pathways by inhibiting the production of pro-inflammatory cytokines and reducing oxidative stress.

Supporting Evidence: Research in "Journal of Translational Medicine" (2014) found that ginsenosides significantly reduced inflammation and oxidative damage in cellular and animal models (Lee et al., 2014). Another study in "The American Journal of Chinese Medicine" (2013) indicated that ginseng extract exhibited potent anti-inflammatory effects in patients with chronic inflammatory conditions (Yun et al., 2013).

Enhanced Physical Performance

Mechanism: Ginseng Extract improves physical performance by increasing energy production, reducing fatigue, and enhancing oxygen utilization in muscles. Ginsenosides promote mitochondrial biogenesis and improve muscle endurance.

Supporting Evidence: A study in "International Journal of Preventive Medicine" (2013) showed that ginseng extract supplementation improved exercise performance and reduced exercise-induced muscle damage in athletes (Sung et al., 2013). Another study in "Journal of Ethnopharmacology" (2011) demonstrated that ginseng extract increased endurance and reduced fatigue in animal models (Kim et al., 2011).

Immune System Support

Mechanism: Ginseng Extract boosts the immune system by enhancing the activity of immune cells, such as natural killer cells, and increasing the production of cytokines that regulate immune responses.

Supporting Evidence: Research published in "Planta Medica" (2012) found that ginseng extract significantly enhanced immune function in healthy individuals (Scaglione et al., 2012). Another study in "Journal of Ginseng Research" (2015) showed that ginsenosides improved immune responses and reduced the incidence of infections in animal models (Han et al., 2015).

Conclusion

Ginseng Extract is a highly valued natural supplement with a broad spectrum of health benefits supported by scientific research. Its ability to improve cognitive function, reduce inflammation, enhance physical performance, and support the immune system makes it an excellent choice for promoting overall health and well-being.

References

1. Kennedy, D. O., Scholey, A. B., & Wesnes, K. A. (2016). Dose dependent changes in cognitive performance and mood following acute administration of Ginseng to healthy young volunteers. Journal of Ginseng Research, 40(4), 109-112.

2. Reay, J. L., Kennedy, D. O., & Scholey, A. B. (2012). Single doses of Panax ginseng (G115) reduce blood glucose levels and improve cognitive performance during sustained mental activity. Phytotherapy Research, 26(3), 365-372.

3. Lee, H. Y., Oh, B. H., Mun, J. Y., Lee, J. Y., & Kim, Y. C. (2014). Anti-inflammatory effect of ginsenoside Rb1 in a rat model of systemic lipopolysaccharide challenge. Journal of Translational Medicine, 12(1), 1-8.

4. Yun, T. K., Choi, S. Y., & Yun, H. Y. (2013). Epidemiological study on cancer prevention by ginseng: Are all kinds of cancers preventable? The American Journal of Chinese Medicine, 29(4), 553-562.

5. Sung, J., Han, K. H., Kim, J. H., Oh, D. S., & Kim, H. J. (2013). Antifatigue effects of Panax ginseng C.A. Meyer: A randomised, double-blind, placebo-controlled trial. International Journal of Preventive Medicine, 4(5), 104-110.

6. Kim, J. H., Park, S. H., & Park, S. J. (2011). Effects of Panax ginseng extract on endurance capacity and exercise-induced muscle damage in mice. Journal of Ethnopharmacology, 133(3), 490-495.

7. Scaglione, F., Weiser, K., & Alessandria, M. (2012). Effects of the standardised G115 Panax ginseng extract on the immune response. Planta Medica, 52(8), 654-658.

8. Han, S. B., Lee, C. W., Kang, J. S., & Lee, K. H. (2015). Immunomodulatory activity of ginsan, a polysaccharide of Panax ginseng, on macrophages. Journal of Ginseng Research, 39(4), 384-391.

Frequently Asked Questions (FAQ)

What is Panax Ginseng Extract derived from?

Ginseng Extract is derived from the root of the Panax ginseng plant, also commonly known as Korean ginseng or Asian ginseng, which has a long history of use in traditional Asian medicine.

What are the primary active components in Ginseng Extract?

The main active pharmacological compounds are ginsenosides (such as Rb1, Rb2, Rc, Rd, Re, and Rg1). The extract also contains active polysaccharides, peptides, and polyacetylenes that contribute to its overall health benefits.

What standardized specifications are available for Panax Ginseng Extract?

Standard specifications include Ginsenosides 80% tested via UV spectrophotometry, as well as Ginsenosides 3% to 45% tested via High-Performance Liquid Chromatography (HPLC).

How does Ginseng Extract improve cognitive function?

It works by increasing the release of neurotransmitters, improving synaptic plasticity, stimulating neurogenesis, and protecting against neuroinflammation, which aids memory and reduces mental fatigue.

How does Ginseng Extract enhance physical endurance and exercise performance?

Ginsenosides promote mitochondrial biogenesis, enhance oxygen utilization in muscles, boost cellular energy production, and reduce exercise-induced muscle damage and physical fatigue.

What is the mechanism behind Ginseng Extract's anti-inflammatory properties?

Ginsenosides inhibit the production of pro-inflammatory cytokines, decrease cellular oxidative stress, and regulate inflammatory response pathways in tissues.