Which certifications do UniCare's manufacturing partners hold?

UniCare works with Chinese manufacturers whose quality systems are certified to standards including GMP, EU-GMP, CEP, ISO 9001, ISO 22000 and HACCP. Certification scope varies by product line, and the relevant certificates are shared for each ingredient during supplier qualification.

How are UniCare botanical extracts tested before release?

Each partner factory has independent testing capability. Typical release testing covers marker compound assay by HPLC or UV, residual solvents by GC, pesticide residues by GC-MS/MS, heavy metals (lead, arsenic, mercury, cadmium, copper) by ICP-MS, microscopic and TLC identification, moisture or loss on drying, ash, microbial limits, pH, conductivity and sulfur dioxide residue.

What documents are supplied with each batch?

Each lot is supplied with a batch-specific Certificate of Analysis. Specification sheets, MSDS, methods of analysis and regulatory statements can be provided on request during qualification.

Can UniCare customize ingredient specifications?

Yes. The customized service covers adjustments such as assay level or extract ratio, particle size and packaging format, subject to technical feasibility and regulatory requirements in the destination market.

How can buyers request a catalog or samples?

Buyers can request the product catalog and samples through the Request a Catalog page, by email at info@unicare-bio.com, or by phone at +86-028-85333989.

China Rhodiola Rosea Extract Suppliers, Factory

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China Rhodiola Rosea Extract Suppliers, Factory

Production Method: Extraction
Source: Rhodiola Rosea L., Rhodiola crenulata.
Appearance: Yellowish brown powder

Specifications:

Rosavins 3%
Salidroside 3%-10%

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Product Description

Rhodiola rosea Extract: Benefits and Mechanisms

Rhodiola rosea Extract is derived from the Rhodiola rosea plant, commonly known as golden root or Arctic root. This adaptogenic herb has been used for centuries in traditional medicine to combat fatigue, enhance physical and mental performance, and improve resilience to stress. The primary active compounds in Rhodiola rosea Extract are rosavins and salidroside.

✓ Specifications

Rosavins 3%

Salidroside 3% - 10%

❖ Key Components of Rhodiola rosea Extract

Compound: Rosavin

CAS number: 84954-92-7

Molecular Formula: C₂₀H₂₈O₁₀

Molecular Weight: 428.43

Structural Formula:

Compound: Rosarin

CAS number: 84954-93-8

Molecular Formula: C₂₀H₂₈O₁₀

Molecular Weight: 428.43

Structural Formula:

Compound: Rosin

CAS number: 85026-55-7

Molecular Formula: C₁₅H₂₀O₆

Molecular Weight: 296.32

Structural Formula:

Compound: Salidroside

CAS number: 10338-51-9

Molecular Formula: C₁₄H₂₀O₇

Molecular Weight: 300.30

Structural Formula:

Rosavins: This group of compounds, including rosavin, rosarin, and rosin, is unique to Rhodiola rosea and contributes significantly to its adaptogenic properties. Rosavins help modulate stress response, improve mood, and enhance cognitive function by influencing neurotransmitter levels and supporting mitochondrial health.

Salidroside: This bioactive compound is a potent antioxit and anti-inflammatory . Salidroside protects against oxidative stress, supports energy production, and promotes neuroprotection. It also enhances physical performance by improving muscle oxygenation and reducing fatigue.

🛡 Stress Reduction and Adaptogenic Properties

Mechanism: Rhodiola rosea Extract helps the body adapt to stress by modulating the hypothalamic-pituitary-adrenal (HPA) axis and increasing the resistance to stress. Rosavins and salidroside contribute to balancing neurotransmitter levels and reducing cortisol levels.

Supporting Evidence: A study in "Phytomedicine" (2012) showed that Rhodiola rosea Extract significantly reduced symptoms of stress and improved mental performance in subjects with stress-related fatigue (Panossian et al., 2012). Another study in "Journal of Ethnopharmacology" (2010) demonstrated that Rhodiola supplementation lowered cortisol response to stress (Olsson et al., 2010).

🧠 Cognitive Enhancement

Mechanism: The neuroprotective effects of Rhodiola rosea Extract are attributed to its ability to increase brain levels of serotonin, dopamine, and norepinephrine. Rosavins and salidroside protect neurons from oxidative stress and enhance mitochondrial function, leading to improved cognitive function.

Supporting Evidence: Research in "Frontiers in Pharmacology" (2018) found that Rhodiola rosea Extract improved memory and learning abilities in animal models of cognitive impairment (Liao et al., 2018). Another study in "Current Clinical Pharmacology" (2012) indicated that Rhodiola supplementation enhanced cognitive function and reduced mental fatigue in humans (Darbinyan et al., 2012).

⚡ Physical Performance and Fatigue Reduction

Mechanism: Rhodiola rosea Extract enhances physical endurance and reduces fatigue by increasing ATP production and improving oxygen utilization. Rosavins and salidroside also have anti-inflammatory properties that aid in muscle recovery.

Supporting Evidence: A study published in "International Journal of Sport Nutrition and Exercise Metabolism" (2004) showed that Rhodiola supplementation improved exercise performance and reduced perceived exertion in athletes (De Bock et al., 2004). Another study in "Planta Medica" (2009) found that Rhodiola rosea Extract decreased fatigue and improved endurance in healthy volunteers (Spasov et al., 2009).

✦ Conclusion

Rhodiola rosea Extract is a potent adaptogen with a wide range of health benefits supported by scientific research. Its ability to reduce stress, enhance cognitive function, and improve physical performance makes it an excellent addition to health and wellness regimens. Rich in rosavins and salidroside, Rhodiola rosea Extract is well-researched and effective for promoting overall well-being.

📖 References

1. Panossian, A., Wikman, G., & Sarris, J. (2012). Rosenroot (Rhodiola rosea): Traditional use, chemical composition, pharmacology and clinical efficacy. Phytomedicine, 19(7), 481-493.

2. Olsson, E. M., von Schéele, B., Panossian, A. G., & Åslund, H. G. (2010). A randomized double-blind placebo-controlled parallel-group study of the standardised extract SHR-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Journal of Ethnopharmacology, 132(3), 414-423.

3. Liao, L., Xie, B., Zhou, W., Lin, X., & Ren, Z. (2018). Rhodiola rosea L. and its active compound salidroside delay chronic stress-induced brain aging by promoting mitochondrial-dependent autophagy in rats. Frontiers in Pharmacology, 9, 704.

4. Darbinyan, V., Aslanyan, G., Amroyan, E., Gabrielyan, E., Malmström, C., & Panossian, A. (2012). Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression. Current Clinical Pharmacology, 2(2), 163-168.

5. De Bock, K., Eijnde, B. O., Ramaekers, M., & Hespel, P. (2004). Acute Rhodiola rosea intake can improve endurance exercise performance. International Journal of Sport Nutrition and Exercise Metabolism, 14(3), 298-307.

6. Spasov, A. A., Wikman, G. K., Mandrikov, V. B., Mironova, I. A., & Neumoin, V. V. (2009). A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Planta Medica, 66(02), 152-157.

? Frequently Asked Questions (FAQ)

Q: What is Rhodiola rosea Extract?

Rhodiola rosea Extract is a natural botanical extract derived from the root of the Rhodiola rosea plant, widely recognized for its adaptogenic properties that assist the body in adapting to mental and physical stress.

Q: What are the primary active markers in Rhodiola rosea Extract?

The main bioactives are rosavins (including rosavin, rosarin, and rosin) and salidroside, which are standardized to guarantee optimal biological efficacy.

Q: How does Rhodiola rosea alleviate stress and fatigue?

It functions by modulating the hypothalamic-pituitary-adrenal (HPA) axis, balancing essential neurotransmitters, optimizing ATP generation, and reducing cortisol levels triggered by stress.

Q: What standardized specifications are commonly available?

Standardized specifications typically feature Rosavins at 3% and Salidroside levels ranging from 3% to 10%.

Q: Can Rhodiola rosea enhance exercise performance?

Yes, clinical and pharmacological studies show that it boosts physical endurance and eases exercise exhaustion through improved oxygen utilization and cellular energy output.